Blood Plasma Arlington,tx If A Person Cannot Make Insulin Or Cannot Respond To Insulin, Will The Blood Plasma Become Hypertonic?

If a person cannot make insulin or cannot respond to insulin, will the blood plasma become hypertonic? - blood plasma arlington,tx

Insulin increases the number of transport proteins that facilitate the entry of glucose into a cell. If a person does not produce insulin or does not respond, use of insulin, what happens?
A. The glucose accumulates in the blood
B. The plasma is hypertonic
C. The plasma is hypotonic.
D. The cells have to use an alternative energy source, because the glucose can not penetrate.
E. The cells lose water in the plasma.